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王英

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suffrutines a and b: a pair of z/e isomeric indolizidine alkaloids from the roots of flueggea suffruticosa

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angewandte chemie-international edition,2014,53(23):5796-5799 | 2014年06月01日 | 10.1002/anie.201400048

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摘要/描述

suffrutines a (1) and b (2), a pair of novel photochemical z/e isomeric indolizidine alkaloids, with a unique and highly conjugated c-20 skeleton, were isolated from the roots of flueggea suffruticosa. the structures were elucidated by extensive analysis of nmr spectra and single-crystal x-ray diffraction. the light-induced isomerization and hypothetical biogenetic pathway to 1 and 2, as well as their activity for regulating the morphology of neuro-2a cells are also discussed.

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