enlightening point of view based on potassium channel “origami windmill” model，成果详细信息-凯发网

applying the k channel origami windmill model principle, the whole process of action potential generation of nerve fiber cells and cardiomyocytes is explained reasonably. its core view is: cell action potential decline phase, dominated by influx of potassium ions. this is contrary to the core idea of the traditional theory—ionic theory. according to ionic theory, cell action potential decline phase, dominated by outflow of k ions. in the face of such two opposing views, the author traces back to the source, combing and commenting on the basic theoretical research on the production mechanism of cell bioelectricity generation and the results of classical basic experiments. and a series of enlightening viewpoints are produced：1. ionic theory has its preexistence deficiency; 2. there are principle defects in ghk equation and h-h equation; 3. ion channels may “same direction sharing”; 4. sodium-potassium pumps, calcium pumps and so on may not exist. the thesis's point is falsifiable. if “cell action potential decline stage, dominated by outflow of k ions” can be proved, all the points in this paper will not be true. on the contrary, the series of enlightening views in this paper will inevitably lead to a revolution in the field of life science. the viewpoint of this paper is not only closely related to the causes of human major diseases, treatment principles and methods, but also may have a profound impact on the future research direction of life science researchers.